75000 - Document - Document and Entity Information
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75010 - Statement - Consolidated balance sheets
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75020 - Statement - Consolidated balance sheets (Parenthetical)
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75030 - Statement - Consolidated statements of operations and comprehensive loss
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75040 - Statement - Consolidated statements of operations and comprehensive loss 2
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75050 - Statement - Consolidated statements of redeemable convertible preferred stock and stockholders' equity (deficit)
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75060 - Statement - Consolidated statements of redeemable convertible preferred stock and stockholders' equity (deficit) (Parenthetical)
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75070 - Statement - Consolidated statements of cash flows
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75080 - Statement - Consolidated statements of cash flows 2
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75090 - Statement - Consolidated statements of cash flows (Parenthetical)
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75100 - Disclosure - Cybersecurity Risk Management, Strategy, and Governance
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995455 - Disclosure - Nature of the Business and Basis of Presentation
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995465 - Disclosure - Summary of Significant Accounting Policies
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995475 - Disclosure - Fair Value Measurements
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995485 - Disclosure - Prepaid Expenses and Other Current Assets
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995495 - Disclosure - Property and Equipment, Net
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995505 - Disclosure - Accrued expenses and other current liabilities
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995515 - Disclosure - Leases
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995525 - Disclosure - Redeemable Convertible Preferred Stock
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995535 - Disclosure - Common Stock
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995545 - Disclosure - Stock-based Compensation
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995555 - Disclosure - Income Taxes
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995565 - Disclosure - Net loss per share
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995575 - Disclosure - Commitments and contingencies
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995585 - Disclosure - License Agreements
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995595 - Disclosure - Revenue
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995605 - Disclosure - Related Parties
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995615 - Disclosure - Employee Benefit Plan
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995625 - Disclosure - Segment Reporting
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995635 - Disclosure - Subsequent Events
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995645 - Disclosure - Summary of Significant Accounting Policies (Policies)
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995655 - Disclosure - Summary of Significant Accounting Policies (Tables)
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995665 - Disclosure - Fair Value Measurements (Tables)
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995675 - Disclosure - Prepaid Expenses and Other Current Assets (Tables)
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995685 - Disclosure - Property and Equipment, Net (Tables)
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995695 - Disclosure - Accrued expenses and other current liabilities (Tables)
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995705 - Disclosure - Leases (Tables)
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995715 - Disclosure - Redeemable Convertible Preferred Stock (Tables)
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995725 - Disclosure - Stock-based Compensation (Tables)
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995735 - Disclosure - Income Taxes (Tables)
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995745 - Disclosure - Net Loss per Share (Tables)
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995755 - Disclosure - Segment Reporting (Tables)
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995765 - Disclosure - Nature of the Business and Basis of Presentation - Additional Information (Details)
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995775 - Disclosure - Summary of Significant Accounting Policies - Additional Information (Details)
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995785 - Disclosure - Summary of Significant Accounting Policies - Schedule of Estimated Useful Life of Each Asset (Details)
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995795 - Disclosure - Fair Value Measurements - Schedule of Financial Assets and Liabilities Measured at Fair Value (Details)
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995805 - Disclosure - Fair Value Measurements - Schedule of Short-Term Investments (Details)
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995815 - Disclosure - Fair Value Measurements - Schedule of Contractual Maturities of Short-term Investments (Details)
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995825 - Disclosure - Fair Value Measurements - Additional Information (Details)
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995835 - Disclosure - Fair Value Measurements - Schedule of Assumptions Used in Option-Pricing Model to Determine Fair Value of Series B Preferred Stock Tranche Right Liability (Details)
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995845 - Disclosure - Fair Value Measurements - Roll-forward of Fair Value of the Series A and Series B Preferred Stock Tranche Right Liability Using Level 3 Inputs (Details)
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995855 - Disclosure - Prepaid Expenses and Other Current Assets - Schedule of Prepaid Expenses and Other Current Assets (Details)
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995865 - Disclosure - Property and Equipment, Net - Schedule of Property Plant and Equipment, Net (Details)
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995875 - Disclosure - Property and Equipment, Net - Additional Information (Details)
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995885 - Disclosure - Accrued expenses and other current liabilities - Schedule of Accrued Expenses and Other Current Liabilities (Details)
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995895 - Disclosure - Leases - Additional Information (Details)
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995905 - Disclosure - Leases - Summary of Components of Lease Cost (Details)
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995915 - Disclosure - Leases - Schedule of Supplemental Disclosure Cash Flow Information Related to Leases (Details)
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995925 - Disclosure - Leases - Schedule of Weighted Discount Rate and Remaining Lease Term (Details)
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995935 - Disclosure - Leases - Schedule of Maturities of Operating Lease Liabilities (Details)
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995945 - Disclosure - Leases - Schedule of Maturities of Operating Lease Liabilities (Details) 2
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995955 - Disclosure - Redeemable Convertible Preferred Stock - Additional Information (Details)
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995965 - Disclosure - Common Stock - Additional Information (Details)
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995975 - Disclosure - Stock-based Compensation - Additional Information (Details)
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995985 - Disclosure - Stock-based Compensation - Schedule of Assumptions Used in Black-Scholes Option-pricing Model to Determine the Fair Value of Stock Options Granted (Details)
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995995 - Disclosure - Stock-based Compensation - Summary of Stock Options Activity (Details)
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996005 - Disclosure - Stock-based compensation - Schedule of Classification of Stock-based Compensation in Condensed Consolidated Statements of Operations and Comprehensive Loss (Details)
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996015 - Disclosure - Income Taxes - Additional Information (Details)
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996025 - Disclosure - Income Taxes - Summary of Effective Income Tax Rate Reconciliation (Details)
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996035 - Disclosure - Income Taxes - Summary of Components of Deferred Tax Asset and Liabilities (Details)
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996045 - Disclosure - Income Taxes - Summary of Valuation Allowance (Details)
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996055 - Disclosure - Net Loss per Share - Summary of Basic and Diluted Net Loss per Share Attributable to Common Stockholders (Details)
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996065 - Disclosure - Net Loss per Share - Schedule of Dilutive Securities Excluded from Calculation of Diluted Net Loss Per Share (Details)
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996075 - Disclosure - Commitments and Contingencies - Additional Information (Details)
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996085 - Disclosure - License Agreements - Additional Information (Details)
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996095 - Disclosure - Revenue - Additional Information (Details)
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996105 - Disclosure - Related Parties - Additional Information (Details)
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996115 - Disclosure - Employee Benefit Plan - Additional Information (Details)
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996125 - Disclosure - Segment Reporting - Additional Information (Details)
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996135 - Disclosure - Segment Reporting - Schedule of Segment Net Loss, Including Disaggregated Components of Operating Expenses (Details)
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996145 - Disclosure - Subsequent Events - Additional Information (Details)
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Weighted Average Exercise Price, Forfeited or expired
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures and Expirations in Period, Weighted Average Exercise Price
Segments [Domain]
Dividends, Preferred Stock
Dividends, Preferred Stock, Total
Cash dividend declared or paid
Deferred Tax Assets, Gross [Abstract]
Deferred tax assets:
Asthma Indication [Member]
Asthma indication.
Asthma Indication
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Deferred Tax Liability Right Of Use Asset
Deferred tax liability right of use asset
ROU asset
ROU asset
Preferred Stock, Shares Issued
Preferred stock, shares issued
Fair value at ending balance
Fair value at beginning balance
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability Value
Accounts payable
Increase (Decrease) in Accounts Payable
Increase (Decrease) in Accounts Payable, Total
Supplemental disclosure of non-cash investing and financing activities:
Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract]
Due within one year
Debt Securities, Available-for-Sale, Fair Value, Maturity, Allocated and Single Maturity Date, Year One
Plan Name [Axis]
Research and Development Expense [Abstract]
Research and development:
Equity [Abstract]
Entity Current Reporting Status
Entity Current Reporting Status
U.S. Government Agency Bonds
US Government Agencies Debt Securities [Member]
Operating expenses:
Operating Expenses [Abstract]
Level 2
Fair Value, Inputs, Level 2 [Member]
Total deferred tax assets - net of valuation allowance
Deferred Tax Assets, Net of Valuation Allowance
Commitments and Contingencies
Commitments and Contingencies Disclosure [Text Block]
Common stock, shares authorized
Common Stock, Shares Authorized
Massachusetts
MASSACHUSETTS
Redeemable convertible preferred stock, par value
Temporary Equity, Par or Stated Value Per Share
License agreement, royalty payments.
License agreement, royalty payments
License Agreement Royalty Payments
Document Fiscal Period Focus
Accounting Standards Update 2023-09 [Member]
ASU 2023-09
Revenue from Contract with Customer [Abstract]
Entity Shell Company
Entity Shell Company
Legal Entity of Counterparty, Type [Axis]
Convertible preferred stock, shares outstanding
Temporary equity, ending balance, shares
Temporary equity, beginning balance, shares
Preferred Stock Outstanding
Redeemable convertible preferred stock, shares outstanding
Fair value of Series B preferred stock tranche right liability at issuance
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Issuances
Segment Information
Segment Reporting, Policy [Policy Text Block]
Cash and cash equivalents
Cash and Cash Equivalent
Cash and Cash Equivalents, at Carrying Value, Total
Denominator:
Weighted Average Number of Shares Outstanding Reconciliation [Abstract]
Professional Fees And Other Research And Development Expense
Professional fees and other research and development expense.
Professional fees and other
Stock Issued During Period, Shares, Conversion of Units
Conversion of convertible preferred stock to common stock upon closing of initial public offering, shares
Cybersecurity Risk Management, Strategy, and Governance [Abstract]
Common stock, shares issued
Common Stock, Shares, Issued
Cybersecurity Risk Management Positions or Committees Responsible Report to Board [Flag]
Cybersecurity Risk Board of Directors Oversight [Text Block]
Lease description
Lessee, Operating Lease, Description
Statement [Table]
Gross proceeds from issuance of preferred stock
Proceeds from Issuance of Redeemable Convertible Preferred Stock
Restricted cash
Restricted Cash, Noncurrent
Right-of-use asset obtained in exchange for operating lease liability
Right-of-Use Asset Obtained in Exchange for Operating Lease Liability
Right-of-use assets obtained in exchange for new operating lease liabilities
Weighted-average grant-date fair value of options granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Change in Accounting Estimate [Line Items]
Issuance of Series A redeemable convertible preferred stock in connection with the settlement of the tranche right liability
Issuance Of Series A Redeemable Convertible Preferred Stock In Connection With Settlement Of Tranche Right Liability
Issuance of series a redeemable convertible preferred stock in connection with settlement of tranche right liability.
Statement [Line Items]
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Expirations in Period, Weighted Average Exercise Price
Weighted Average Exercise Price, Cancelled
License agreement, termination written notice period
License Agreement Termination Written Notice Period
License agreement, termination written notice period.
Entity Filer Category
Entity Filer Category
Selling, General and Administrative Expenses, Policy [Policy Text Block]
General and Administrative Expenses
Liabilities and Equity
Total liabilities and stockholders' equity
Payables and Accruals [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Weighted Average Exercise Price, Options exercisable December 31, 2025
Restructuring Type [Axis]
Long-Lived Tangible Asset [Axis]
Valuation Allowance, Deferred Tax Asset, Increase (Decrease), Amount
Increases recorded to income tax provision
Increases recorded to income tax provision
Cybersecurity Risk Third Party Oversight and Identification Processes [Flag]
Cash equivalents
Cash and Cash Equivalents, Fair Value Disclosure
Deferred Tax Assets, Valuation Allowance
Valuation allowance
Valuation allowance
Valuation allowance
Valuation allowance at beginning of year
Valuation allowance at beginning of year
Effective federal tax rate
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent
US Federal statutory income tax rate
U.S. federal statutory income tax rate
Issued price per share
Shares Issued, Price Per Share
Subsequent Event [Line Items]
Cybersecurity Risk Management Third Party Engaged [Flag]
Documents Incorporated by Reference
Documents Incorporated by Reference [Text Block]
Goodwill
Goodwill, Ending Balance
Goodwill, Beginning Balance
Goodwill, Total
Effective Income Tax Rate Reconciliation, Percent
Effective Income Tax Rate Reconciliation, Percent, Total
Effective income tax rate
Effective income tax rate
Stock Options to Purchase Common Stock
Manufacturing Costs
Manufacturing costs
Interest income
Investment Income, Interest
Income Tax Jurisdiction [Axis]
Gross proceeds
Proceeds from Convertible Debt
Geographical [Domain]
Defined Contribution Plan [Abstract]
Numerator:
Net Income (Loss) Available to Common Stockholders, Basic [Abstract]
Percentage of original issue price plus accrued return
Percentage of Original Issue Price plus Accrued Return
Percentage of original issue price plus accrued return.
Related Party
Related Party [Member]
Issuance Of Preferred Stock Allocated To Tranche Right Liability
Issuance of preferred stock allocated to tranche right liability.
Series B issuance costs allocated to tranche right liability
Summary of Significant Accounting Policies
Significant Accounting Policies [Text Block]
Property, Plant and Equipment [Line Items]
Stock options, granted
Number of Options, Granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Disaggregation of Revenue [Table]
Preferred stock cumulative dividends
Redeemable convertible preferred stock cumulative dividends
Redeemable convertible preferred stock cumulative dividends
Redeemable Preferred Stock Dividends
Cybersecurity Risk Management, Strategy, and Governance [Table]
Summary of Basic and Diluted Net Loss per Share Attributable to Common Stockholders
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
Operating lease effective date
Lessee Operating Lease Effective Date
Lessee operating lease effective date.
Series B Redeemable Convertible Preferred Stock
Series B Redeemable Convertible Preferred Stock [Member]
Series B redeemable convertible preferred stock
Gross cash proceeds
Gross proceeds from issuance of preferred stock
Proceeds from Issuance of Preferred Stock and Preference Stock
Schedule of Contractual Maturities of Short-term Investments
Investments Classified by Contractual Maturity Date [Table Text Block]
Net loss per share attributable to common stockholders, basic
Earnings Per Share, Basic
Earnings Per Share, Basic, Total
Fair value of convertible preferred stock
Fair Value Of Convertible Preferred Stock
Fair Value Of Convertible Preferred Stock
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Number of Options, Outstanding as of December 31, 2024
Number of Options, Outstanding as of December 31, 2025
Royalty payment term upon first commercial sale
Royalty Payment Term Upon First Commercial Sale
Royalty payment term upon first commercial sale.
Interest income
Interest Income (Expense), Nonoperating
Interest Income (Expense), Nonoperating, Total
Total current liabilities
Liabilities, Current
Tax Credit Carryforward Expiration Years
Tax Credit Carryforward Expiration Years
Expiration years
Percentage of limited utilization of taxable income.
Percentage of limited utilization of taxable income
Adjustments to reconcile net loss to net cash used in operating activities:
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract]
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block]
Roll-forward of Fair Value of the Series A and Series B Preferred Stock Tranche Right Liability Using Level 3 Inputs
Milestone Shares
Milestone Shares [Member]
Milestone Shares [Member]
Useful Life, Term, Description [Domain]
Domestic Tax Jurisdiction [Member]
Federal
Effective Income Tax Rate Reconciliation [Table]
Accounting Standards Update [Axis]
Equity, Attributable to Parent [Abstract]
Stockholders' equity (deficit):
Entity Small Business
Entity Small Business
Preferred Stock Tranche Right Liability (Series B)
Preferred Stock Tranche Right Liability Series B [Member]
Preferred stock tranche right liability series b.
Accumulated deficit
Retained Earnings (Accumulated Deficit)
Retained Earnings (Accumulated Deficit), Total
Stock-based compensation
Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-Based Compensation Cost
Entity Well-known Seasoned Issuer
Entity Well-known Seasoned Issuer
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Number Of Options, Forfeited
Net proceeds from issuance of initial public offering
Proceeds from issuance of Initial Public Offering
Proceeds from initial public offering, net of underwriters discounts and commissions
Sale of stock, price per share
Sale of Stock, Price Per Share
Aggregate intrinsic value of stock options exercised
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value
Research And Development Personnel Expense
Research and development personnel expense.
Personnel expenses
Stock-based Compensation
Share-Based Payment Arrangement [Text Block]
Purchases of short-term investments
Payments to Acquire Short-Term Investments
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Eight Nine Zero Winter Street in Waltham, Massachusetts [Member]
890 Winter Street in Waltham, Massachusetts.
890 Winter Street in Waltham, Massachusetts
License agreement, annual payment.
License agreement, annual payment
License Agreement Annual Payment
Preferred stock, par value second closing
Preferred Stock Par Value Per Share Second Closing
Preferred Stock Par Value Per Share Second Closing
Leases [Abstract]
Short-Term Investments
Short Term Investments [Policy Text Block]
Short term investments.
Lessee, Lease, Description [Line Items]
Amendment Flag
U.S. federal statutory income tax rate
Effective Income Tax Rate Reconciliation at Federal Statutory Income Tax Rate, Amount
Effective Income Tax Rate Reconciliation Change In Fair Value Of Financial Instruments
Effective income tax rate reconciliation change in fair value of financial instruments
Change in fair value of financial instruments
Change in fair value of financial instruments
Net Change In Initial Public Offering Costs Accrued But Not Paid
Net change in initial public offering costs accrued but not paid.
Initial public offering costs included in accounts payable
Common Stock
Common Stock [Text Block]
Common Stock.
Chief Executive Officer
Chief Executive Officer
Net Loss Per Share
Earnings Per Share, Policy [Policy Text Block]
Liabilities and Equity [Abstract]
Liabilities and Stockholders' Equity
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Net cash used in operating activities
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation
Operating lease liabilities
Operating lease liabilities
Increase (Decrease) in Operating Lease Liability
Common Stock
Common Stock [Member]
2021 Stock Option and Grant Plan
Two Thousand Twenty One Stock Option and Grant Plan [Member]
Two thousand twenty one stock option and grant plan.
Cybersecurity Risk Role of Management [Text Block]
Tax Credit Carryforward, Amount
Tax credit
Defined Contribution Plan, Employer Discretionary Contribution Amount
Employer benefit plan contribution
Weighted Average Exercise Price, Granted
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Interest receivable
Interest Receivable, Current
Rent payment, year three
Lessee, Operating Lease, Liability, to be Paid, Year Three
2027
Less: Accumulated depreciation and amortization
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Ending Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Beginning Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Total
Debt Securities, Available-for-Sale [Line Items]
ASU 2024-03
Accounting Standards Update 2024-03 [Member]
Entity Address, Address Line One
Entity Address, Address Line One
Total deferred tax liabilities
Deferred Tax Liabilities, Gross
Total deferred tax liabilities
Change in Accounting Principle, Accounting Standards Update, Immaterial Effect [true false]
Change in accounting principle accounting standards update immaterial effect [true false]
Schedule of Assumptions Used in Black-Scholes Option-pricing Model to Determine the Fair Value of Stock Options Granted
Schedule of Assumptions Used in Option-Pricing Model to Determine Fair Value of Series B Preferred Stock Tranche Right Liability
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Fair Value Hierarchy and NAV [Axis]
Earnings Per Share [Abstract]
Income Tax, Policy [Policy Text Block]
Income Taxes
Liabilities recorded for loss contingencies
Loss Contingency Accrual
Loss Contingency Accrual, Ending Balance
Loss Contingency Accrual, Beginning Balance
Temporary equity, ending balance
Temporary equity, beginning balance
Carrying Value
Temporary Equity, Carrying Amount, Attributable to Parent
Redeemable convertible preferred stock (Series A, B), $0.001 par value; no shares and 31,764,693 shares authorized at December 31, 2024 and December 31, 2023, respectively; no shares and 22,941,170 shares issued and outstanding at December 31, 2024 and December 31, 2023, respectively; aggregate liquidation preference of $0 and $267,718 at December 31, 2024 and December 31, 2023, respectively
Cybersecurity Risk Materially Affected or Reasonably Likely to Materially Affect Registrant [Flag]
Supplemental cash flow information:
Supplemental Cash Flow Information [Abstract]
Foreign Currency Gains and Losses
Foreign Currency Transactions and Translations Policy [Policy Text Block]
Capitalized research and development expense
Deferred Tax Assets Capitalized Research And Development Expense
Deferred tax assets capitalized research and development expense.
Change in Accounting Estimate [Table]
Investment Type [Axis]
Underwriting discounts and commissions
Payments for Underwriting Expense
Operating lease right-of-use assets
Operating Lease, Right-of-Use Asset
Total deferred tax assets before valuation allowance
Deferred Tax Assets, Gross
Cybersecurity Risk Board Committee or Subcommittee Responsible for Oversight [Text Block]
Document Type
Document Type
General And Administrative Personnel Expense
General and administrative personnel expense.
Personnel expenses
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Entity Central Index Key
Entity Central Index Key
Schedule of Short-Term Investments
Debt Securities, Available-for-Sale [Table Text Block]
Cybersecurity Risk Process for Informing Board Committee or Subcommittee Responsible for Oversight [Text Block]
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation
Net increase (decrease) in cash, cash equivalents and restricted cash
Subsequent Event Type [Domain]
Common Stock Issuable Upon Conversion
Dilutive securities excluded from calculation of diluted net loss per share
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Two Thousand Twenty Four Stock Option and Incentive Plan and Two Thousand Twenty One Stock Option and Grant Plan [Member]
Two thousand twenty four stock option and incentive plan and two thousand twenty one stock option and grant plan.
2024 Stock Option and Incentive Plan and 2021 Stock Option and Grant Plan
Interim Second Closing
Interim Second Closing [Member]
Interim Second Closing [Member]
Common stock, par value
Common Stock, Par or Stated Value Per Share
Accounting Standards Update [Domain]
Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent
Total other comprehensive income (loss)
Total other comprehensive income (loss)
Weighted-Average Remaining Contractual Term, Outstanding
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Amortized Cost
Amortized Cost
Debt Securities, Available-for-Sale, Amortized Cost
Total available-for-sale securities
Shor-term investments
Fair Value
Debt Securities, Available-for-Sale
Estimated Useful Life of Each Asset [Table Text Block]
Estimated useful life of each asset.
Schedule of Estimated Useful Life of Each Asset
Document Financial Statement Error Correction [Flag]
Document Financial Statement Error Correction
Number of Options, Exercised
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Other
Other Prepaid Expense, Current
Initial Public Offering, Underwriting Fee
Initial public offering, underwriting fee.
Initial public offering, underwriting fee
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Current Fiscal Year End Date
Current Fiscal Year End Date
Fair Value, by Balance Sheet Grouping [Table]
Entity Address, State or Province
Entity Address, State or Province
Prepaid Expenses and Other Current Assets
Prepaid Expense And Other Assets Current [Text block]
Prepaid Expense And Other Assets Current.
Preferred Stock, Shares Outstanding
Preferred Stock, Shares Outstanding, Ending Balance
Preferred Stock, Shares Outstanding, Beginning Balance
Preferred stock, shares outstanding
Comprehensive loss
Comprehensive Income (Loss), Net of Tax, Attributable to Parent
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax
Gross Unrealized Gains
Research and Development Expenses
Research and Development Expense, Policy [Policy Text Block]
Common stock reserved for future issuance
Shares of common stock reserved for issuance
Common Stock, Capital Shares Reserved for Future Issuance
Geographical [Axis]
Chief Operating Officer
Chief Operating Officer [Member]
Preferred stock shares converted to common stock
Conversion of Stock, Shares Converted
Conversion of convertible preferred stock to common stock upon closing of initial public offering
Preferred stock tranche right liability settled
Preferred Stock Tranche Right Liability Settled
Preferred Stock Tranche Right Liability Settled
Classification and Accretion of Redeemable Convertible Preferred Stock [Policy Text Block]
Classification and accretion of redeemable convertible preferred stock.
Classification and Accretion of Redeemable Convertible Preferred Stock
Sale of shares of common stock to public at price per share
Sale of Shares of Common Stock to Public at Price Per Share
Sale of shares of common stock to public at price per share.
Other General and Administrative Expense
Other
Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Amount
State and local income taxes, net of federal income tax effect
Schedule of Classification of Stock-based Compensation in Condensed Consolidated Statements of Operations and Comprehensive Loss
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Other, Amount
Nontaxable or nondeductible items. Other
Comprehensive Income, Policy [Policy Text Block]
Comprehensive Loss
Percentage of accruing dividend
Percentage of Accruing Dividend
Percentage of accruing dividend.
Accrued expenses and other current liabilities
Accounts Payable, Accrued Liabilities, and Other Liabilities Disclosure, Current [Text Block]
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
Summary of Components of Deferred Tax Asset and Liabilities
Percentage of accrued return shall not exceed original issue price
Percentage of Accrued Return Shall not Exceed Original Issue Price
Percentage of accrued return shall not exceed original issue price.
License Agreements
Collaborative Arrangement Disclosure [Text Block]
Performance-based Stock Options
Performance Shares [Member]
Preferred stock tranche right liability
Preferred Stock Tranche Right Liability
Preferred stock tranche right liability.
Subsequent Events
Subsequent Event [Member]
Property, Plant and Equipment [Abstract]
Research and development tax credit carryforward
Deferred Tax Assets, Tax Credit Carryforwards, Research
Proceeds from the issuance of preferred stock
Proceeds from Issuance of Convertible Preferred Stock
Proceeds from the issuance of Series B redeemable convertible preferred stock, net of issuance costs paid
Antidilutive Securities [Axis]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Expirations in Period
Number of Options, Cancelled
State and Local Jurisdiction [Member]
State
Related Party Transaction [Axis]
Accumulated Other Comprehensive Income (Loss)
AOCI Attributable to Parent [Member]
Cash and Cash Equivalents [Domain]
Preferred Stock, Value, Issued
Preferred stock, $0.001 par value; 10,000,000 shares authorized at December 31, 2025 and December 31, 2024; no shares issued and outstanding at December 31, 2025 and December 31, 2024
Redeemable Convertible Preferred Stock
Redeemable Convertible Preferred Stock [Text Block]
Redeemable convertible preferred stock.
Minimum
Minimum [Member]
Financial Instrument [Axis]
Current assets:
Assets, Current [Abstract]
Level 3
Fair Value, Inputs, Level 3 [Member]
Segment Reporting [Abstract]
Schedule of Financial Assets and Liabilities Measured at Fair Value
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]
Current liabilities:
Liabilities, Current [Abstract]
Conversion terms for preferred stock
Preferred Stock, Convertible, Terms
Accrued offering costs
Accrued Offering Costs Current
Accrued offering costs current.
Related Party Transactions [Abstract]
Ending balance, shares
Beginning balance, shares
Shares, Outstanding
Operating Loss Carryforwards
Net operating loss carryforwards
Related party accounts receivable
Accounts Receivable, after Allowance for Credit Loss, Current
Accounts receivable
Redeemable convertible preferred stock issuance costs
Redeemable Convertible Preferred Stock Issuance Costs
Redeemable convertible preferred stock issuance costs.
Proceeds from Stock Plans
Proceeds from issuance of common stock under employee stock purchase plan
Commitments and contingencies (Note 13)
Commitments and Contingencies
Lessee, Leases [Policy Text Block]
Operating Leases
General and Administrative
General and Administrative Expense [Member]
Operating Lease, Liability
Present value of lease liabilities
Series B redeemable convertible preferred stock issuance costs
Series B Redeemable Convertible Preferred Stock Issuance Costs
Series B redeemable convertible preferred stock issuance costs.
Auditor Firm ID
Auditor Firm ID
Preferred stock, dividend rate per annum
Preferred Stock, Dividend Rate, Percentage
Lessee, Lease, Description [Table]
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Percent
Change in deferred tax asset valuation allowance
Change in deferred tax asset valuation allowance
Change in valuation allowance
Purchases of property and equipment included in accounts payable and accrued expenses
Capital Expenditures Incurred but Not yet Paid
Net loss
Net loss
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total
Number of board of directors entitled to elect
Number of Board of Directors Entitled to Elect
Number of board of directors entitled to elect.
Cybersecurity Risk Management Positions or Committees Responsible [Text Block]
Weighted-average common shares outstanding, basic
Weighted Average Number of Shares Outstanding, Basic
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value
Intrinsic Value, Options exercisable December 31, 2025
Segment reporting, expense information used by codm, description
Segment reporting, expense information used by codm, description
Stock-based compensation
Effective Income Tax Rate Reconciliation, Tax Expense (Benefit), Share-Based Payment Arrangement, Percent
Stock-based compensation
Incremental stock-based compensation
Share-Based Payment Arrangement, Plan Modification, Incremental Cost
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
Summary of Effective Income Tax Rate Reconciliation
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Segments [Axis]
Long-Lived Tangible Asset [Domain]
Cybersecurity Risk Process for Informing Management or Committees Responsible [Text Block]
Subsequent Events
Subsequent Events [Text Block]
Related Parties
Related Party Transactions Disclosure [Text Block]
Stock-based compensation expense
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition, Total
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Amount
Change in valuation allowance
Ending balance
Beginning balance
Equity, Attributable to Parent
Total stockholders' equity
Preferred stock, par value
Preferred stock, par value (in dollars per share)
Preferred Stock, Par or Stated Value Per Share
Statement of Stockholders' Equity [Abstract]
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]
Type of Restructuring [Domain]
Series A Preferred Stock
Series A Preferred Stock [Member]
Use of Estimates, Policy [Policy Text Block]
Use of Estimates
Over Allotment Option
Over-Allotment Option [Member]
Leasehold Improvements
Leasehold Improvements [Member]
Entity Address, Address Line Two
Entity Address, Address Line Two
Fair Value Measurements
Fair Value Disclosures [Text Block]
Product Information [Line Items]
Schedule of Accrued Expenses and Other Current Liabilities
Schedule of Accrued Liabilities [Table Text Block]
Accrued expenses and other current liabilities
Accrued expenses and other current liabilities
Accrued Liabilities and Other Liabilities
Segment Reporting, CODM, Individual Title and Position or Group Name [Extensible Enumeration]
Plan Name [Domain]
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Settlements
Final settlement of Series B preferred stock tranche right liability
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cybersecurity Risk Materially Affected or Reasonably Likely to Materially Affect Registrant [Text Block]
Impairment, Long-Lived Asset, Held-for-Use
Impairment, Long-Lived Asset, Held-for-Use, Total
Impairment of long-lived assets
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Weighted Average Exercise Price
Weighted Average Exercise Price, Vested and expected to vest December 31, 2025
Nature of the Business and Basis of Presentation
Business Description and Basis of Presentation [Text Block]
Cybersecurity Risk Management Expertise of Management Responsible [Text Block]
Deferred Offering Costs
Deferred Charges, Policy [Policy Text Block]
Lessee, Operating Lease, Liability, to be Paid, Fiscal Year Maturity [Abstract]
Related and Nonrelated Parties [Axis]
Property, Plant and Equipment, Policy [Policy Text Block]
Property and Equipment
Accounting Standards Update [Extensible Enumeration]
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Liabilities Increase Decrease
Fair value, measurement with unobservable inputs reconciliation, recurring basis, liabilities, increase (decrease).
Change in fair value of Series B preferred stock tranche right liability
Conversion of Stock [Line Items]
Area of real estate property
Area of Real Estate Property
Entity Address, City or Town
Entity Address, City or Town
Number of reportable segments
Number of Reportable Segments
Security Exchange Name
Security Exchange Name
Property and equipment, gross
Property, Plant and Equipment, Gross
Schedule of Preferred Stock
Temporary Equity [Table Text Block]
Offering costs
Deferred offering costs
Deferred Offering Costs
Schedule of Supplemental Disclosure Cash Flow Information Related to Leases
Schedule Of Supplemental Disclosure Of Cash Flow Information Related To Leases [Table Text Block]
Schedule of supplemental disclosure of cash flow information for operating leases table.
Antidilutive Securities, Name [Domain]
COPD indication.
COPD Indication [Member]
COPD Indication
Total cash, cash equivalents and restricted cash at end of period
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Ending Balance
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Beginning Balance
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table]
Statistical Measurement [Domain]
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Transfers, Net, Total
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Transfers, Net
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Transfers, Net, Total
Total current assets
Assets, Current
Stock-based compensation
Share-Based Payment Arrangement, Expense
Stock-based compensation expense
Document Period End Date
Document Period End Date
Title and Position [Axis]
Fair Value Hierarchy and NAV [Domain]
ICFR Auditor Attestation Flag
ICFR Auditor Attestation Flag
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Number of Options, Options exercisable December 31, 2025
Stock-based compensation expense - related party, shares
Stock Issued During Period, Shares, Stock Based Compensation Expense To Related Party
Stock issued during period, shares, stock based compensation expense to related party.
Issuance of common stock
Statement of Financial Position [Abstract]
Revenue [Policy Text Block]
Revenue Recognition
Temporary Equity Conversion Of Convertible Preferred Stock To Common Stock Value
Temporary equity conversion of convertible preferred stock to common stock value.
Conversion of convertible preferred stock to common stock upon closing of initial public offering
Conversion of convertible preferred stock to common stock upon closing of initial public offering
Redeemable Convertible Preferred Stock
Redeemable Convertible Preferred Stock [Member]
Cash, cash equivalents and restricted cash at end of period:
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation [Abstract]
Class of Stock [Axis]
Employee Benefit Plan
Compensation and Employee Benefit Plans [Text Block]
In Process Research and Development, Policy [Policy Text Block]
Asset acquisition and acquired in-process research and development expenses
Other offering costs
Other Offering Costs
Other offering costs.
Cybersecurity Risk Management, Strategy, and Governance [Line Items]
Effect of changes in tax laws or rates enacted in the current period
Effective Income Tax Rate Reconciliation, Change in Enacted Tax Rate, Percent
Total liabilities
Liabilities
Issuance of Series A redeemable convertible preferred stock in connection with the settlement of the tranche right liability, shares
Issuance Of Series A Redeemable Convertible Preferred Stock In Connection With Settlement Of Tranche Right Liability Shares
Issuance of series a redeemable convertible preferred stock in connection with settlement of tranche right liability shares.
Financial Instruments [Domain]
Deferred revenue - related party
Increase (Decrease) in Deferred Revenue
Shorter of remaining lease term or estimated useful life
Useful Life, Shorter of Lease Term or Asset Utility [Member]
Rent payment, year two
Lessee, Operating Lease, Liability, to be Paid, Year Two
2026
Schedule of Prepaid Expenses and Other Current Assets
Prepaid Expense and Other Assets, Current [Abstract]
Weighted-average common shares outstanding, diluted
Weighted Average Number of Shares Outstanding, Diluted
Due after one year through two years
Available For Sale Securities Debt Maturities After One Through Two Years Fair value
Available for sale securities debt maturities after one through two years fair value.
Entity File Number
Entity File Number
Unrealized gain (loss) on investments, net of tax
OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax
Unrealized gain (loss) on available-for-sale securities, net of tax
Maturities of short-term investments
Proceeds from Sale, Maturity and Collection of Short-Term Investments
Proceeds from Sale, Maturity and Collection of Short-Term Investments, Total
ASU 2023-07
Accounting Standards Update 2023-07 [Member]
Cover [Abstract]
Cash, Cash Equivalents And Short-term Investments
Cash, Cash Equivalents And Short-term Investments
Cash, cash equivalents and short-term investments
Payments for Repurchase of Initial Public Offering
Payments of initial public offering costs
Prepaid expenses and other current assets
Prepaid expenses and other current assets
Prepaid Expense and Other Assets, Current
Increase in percentage of outstanding number of common stock
Share-Based Compensation Arrangement by Share-Based Payment Award, Percentage of Outstanding Stock Maximum
Investments [Domain]
Summary of Valuation Allowance [Table Text Block]
Summary of Valuation Allowance
U.S. Treasury Bills
US Treasury Securities [Member]
US Treasury Securities
General and Administrative Professional Fees Expenses
General and administrative professional fees expenses.
Professional fees
Number of Operating Segments
Number of operating segments
Sale of Stock [Domain]
Segment Reporting Disclosure [Text Block]
Segment Reporting
General and administrative
General and Administrative Expense
Total general and administrative expenses
Series B Preferred Stock
Series B Preferred Stock [Member]
Lonza license agreement.
Lonza License Agreement
Lonza License Agreement [Member]
Liquidation Preference
Redeemable convertible preferred stock, liquidation preference
Temporary Equity, Liquidation Preference
Stock options vested
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested, Number of Shares
Number of Options, Forfeited or expired
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures and Expirations in Period
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures and Expirations in Period, Total
Subsequent Event [Table]
Shares issued
Share-Based Compensation Arrangement by Share-Based Payment Award, Shares Issued in Period
Original issue price per share
Original Issue Price Per Share
Original issue price per share.
Deferred Tax Assets, Other
Deferred tax assets
Effect of changes in tax laws or rates enacted in the current period
Effective Income Tax Rate Reconciliation, Change in Enacted Tax Rate, Amount
Nature of Operation, Product Information, Concentration of Risk [Table]
Property, Plant and Equipment, Useful Life
Estimated Useful Life
New Accounting Pronouncements, Policy [Policy Text Block]
Recently Adopted/Issued Accounting Pronouncements Not Yet Adopted
Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block]
Schedule of Maturities of Operating Lease Liabilities
Exercisable, termination term
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Termination Term
Share-based compensation arrangement by share-based payment award, options, exercisable, termination term.
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Other, Percent
Nontaxable or nondeductible items, Other
Prepaid employee-related costs
Prepaid employee-related costs.
Income Tax Expense (Benefit), Effective Income Tax Rate Reconciliation, Amount [Abstract]
Operating lease, term of contract
Lessee, Operating Lease, Term of Contract
Common stock, shares outstanding
Common Stock, Shares, Outstanding
Common Stock, Shares, Outstanding, Ending Balance
Common Stock, Shares, Outstanding, Beginning Balance
Operating lease liabilities, current portion
Operating Lease, Liability, Current
Less: operating lease liabilities, current portion
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Depreciation and amortization expense
Depreciation and amortization
Depreciation, Depletion and Amortization
Depreciation, Depletion and Amortization, Total
Schedule Of Weighted Discount Rate And Remaining Lease Term [Table Text Block]
Schedule of weighted discount rate and remaining lease term.
Schedule of Weighted Discount Rate and Remaining Lease Term
Cybersecurity Risk Management Processes Integrated [Flag]
Document Transition Report
Document Transition Report
Deferred Tax Assets, Net
Net deferred tax asset (liability)
Short-term investments
Short-Term Investments
Short-Term Investments, Total
Total operating expenses
Operating Expenses
Research and development
Research and development services
Research and Development Expense
Total research and development expenses
Leases
Lessee, Operating Leases [Text Block]
Convertible Preferred Stock
Preferred stock converted to common stock
Convertible Preferred Stock [Member]
Number of shares held
Shares Held in Employee Stock Option Plan, Allocated
Statement of Cash Flows [Abstract]
Stock Issued During Period, Value, New Issues
Issuance of common stock from initial public offering, net of issuance costs
Summary of Stock Options Activity
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Deferred Tax Assets Accrued Expenses
Deferred tax assets accrued expenses
Accrued expenses
Net Loss per Share
Earnings Per Share [Text Block]
Other
Deferred Tax Liabilities, Other
Other
Computer Equipment [Member]
Computer Equipment
Cybersecurity Risk Management Processes Integrated [Text Block]
Net loss
Net loss
Intrinsic Value, Outstanding
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Operating Lease, Cost
Operating lease cost
Convertible preferred stock converted to common stock
Common Stock Issuable Upon Conversion
Preferred Stock, Convertible, Shares Issuable
Redeemable convertible preferred stock tranche right liability
Redeemable Convertible Preferred Stock Tranche Right Liability
Redeemable convertible preferred stock tranche right liability.
Expected dividends
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Earnings Per Share, Basic, by Common Class, Including Two Class Method [Line Items]
Operating Lease, Payments
Cash paid for amounts included in the measurement of lease liabilities
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Aggregate Intrinsic Value
Intrinsic Value, Vested and expected to vest December 31, 2025
Assets
Assets [Abstract]
Risk-free rate
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Construction in Progress
Construction in Progress [Member]
Prepaid expenses and other assets
Prepaid expenses and other assets
Increase (Decrease) in Prepaid Expense and Other Assets
Document Fiscal Year Focus
Document Fiscal Year Focus
Convertible preferred stock approval by number of directors
Convertible Preferred Stock Approval By Number Of Directors
Convertible preferred stock approval by number of directors.
Deferred offering costs included in accounts payable and accrued expenses
Net Change In Deferred Offering Costs Accrued But Not Paid
Net change in deferred offering costs accrued but not paid.
Cash flows from investing activities:
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract]
Maruho Agreement
Maruho Agreement [Member]
Maruho agreement.
Accounts payable
Accounts Payable, Current
Accounts Payable, Current, Total
Research and Development
Research and Development Expense [Member]
Schedule of Prepaid Expenses and Other Current Assets
Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Table Text Block]
Fair Value Measurements
Fair Value Measurement, Policy [Policy Text Block]
Proceeds from exercises of stock options
Proceeds from Stock Options Exercised
Fair Value Disclosures [Abstract]
Commitments and Contingencies Disclosure [Abstract]
Rent payment, year one
Lessee, Operating Lease, Liability, to be Paid, Year One
2025
Preferred stock cumulative dividends
Net loss attributable to common stockholders
Net Income (Loss) Available to Common Stockholders, Basic
Effective Income Tax Rate Reconciliation [Line Items]
Letter of credit
Long-Term Line of Credit
Long-Term Line of Credit, Total
Series A Redeemable Convertible Preferred Stock
Series A Redeemable Convertible Preferred Stock [Member]
Series A redeemable convertible preferred stock.
Share-Based Payment Arrangement [Abstract]
Assets
Assets, Fair Value Disclosure
Sale of Stock [Axis]
Net cash used in investing activities
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation
Title of 12(b) Security
Title of 12(b) Security
Schedule of Segment Reporting Information, by Segment [Table]
Conversion of convertible preferred stock to common stock upon closing of initial public offering
Stock Issued During Period, Value, Conversion of Units
Weighted Average Exercise Price, Forfeited
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Money Market Funds
Money Market Funds [Member]
Related and Nonrelated Parties [Domain]
Income Taxes
Income Tax Disclosure [Text Block]
Collaborative Arrangement and Arrangement Other than Collaborative [Table]
Preferred stock, shares issued
Preferred Stock Issued
Redeemable convertible preferred stock, shares issued
Changes in operating assets and liabilities:
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract]
Schedule of Property and Equipment, Net
Property, Plant and Equipment [Table Text Block]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Weighted Average Exercise Price, Outstanding as of December 31, 2024
Weighted Average Exercise Price, Outstanding as of December 31, 2025
Income Tax Disclosure [Abstract]
Fair Value, Recurring and Nonrecurring [Table]
Uncertain tax positions
Unrecognized Tax Benefits
Unrecognized Tax Benefits, Ending Balance
Unrecognized Tax Benefits, Beginning Balance
Additional Paid-in Capital
Additional Paid-in Capital [Member]
Measurement Frequency [Domain]
Statement of Income Location, Balance [Axis]
Change in Accounting Principle, Accounting Standards Update, Adoption Date
Change in accounting principle accounting standards update adoption date
Trading Symbol
Trading Symbol
Property and Equipment, Net
Property, Plant and Equipment Disclosure [Text Block]
Related Party Transaction [Table]
Other permanent differences
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Percent
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Percent, Total
Other permanent differences
Subsequent Event Type [Axis]
Accrued employee compensation and benefits
Employee-related Liabilities, Current
Employee-related Liabilities, Current, Total
Stock issued during period shares stock options exercised net of tax withholding.
Exercise of stock options, net of tax withholding, shares
Stock Issued During Period Shares Stock Options Exercised Net Of Tax Withholding
Cash flows from financing activities:
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract]
Expected term (in years)
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Fair Value on Recurring Basis
Fair Value, Recurring [Member]
Entity Ex Transition Period
Lessee, Operating Lease, Liability, to be Paid
Total lease payments
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Less: imputed interest
Less: imputed interest
Effective Income Tax Rate Reconciliation, Tax Credit, Research, Percent
Research and development tax credits
Research and development tax credits
Equity Components [Axis]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Weighted Average Remaining Contractual Term
Weighted-Average Remaining Contractual Term, Vested and expected to vest December 31, 2025
Total other income, net
Nonoperating Income (Expense)
Equity Component [Domain]
Document Annual Report
Document Annual Report
Settlement of preferred stock tranche right liability
Settlement of Preferred Stock Tranche Right Liability
Settlement of preferred stock tranche right liability.
Prepaid Insurance
Prepaid insurance
IPO
IPO [Member]
Postemployment Benefits [Abstract]
Stock Issued During Period, Shares, Employee Stock Purchase Plans
Issuance of common stock under employee stock purchase plan, shares
Other expense, net
Other expense, net
Other nonoperating income expenses
Other nono.perating income expenses
Other offering costs
Other Offering Cost
Other offering cost.
Maximum
Maximum [Member]
Liabilities
Liabilities, Fair Value Disclosure
Statistical Measurement [Axis]
Weighted Average Exercise Price, Exercised
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
CRSwNP Indication [Member]
CRSwNP indication.
CRSwNP Indication
Prepaid Expense, Current, Total
Prepaid research and development expense
Prepaid Expense, Current
Accrued expenses and other current liabilities
Accrued expenses and other current liabilities
Increase (Decrease) in Other Accounts Payable and Accrued Liabilities
Prepaid and Accrued Research and Development Expenses [Policy Text Block]
Prepaid and Accrued Research and Development Expenses.
Prepaid and Accrued Research and Development Expenses
Common Stock, Value, Issued
Common stock, $0.001 par value; 500,000,000 shares authorized at December 31, 2025 and December 31, 2024; 54,237,750 and 53,603,398 shares issued and outstanding at December 31, 2025 and December 31, 2024, respectively
Preferred Stock Tranche Right Liabilities [Policy Text Block]
Preferred stock tranche right liabilities.
Preferred Stock Tranche Right Liabilities
Lab Equipment
Equipment [Member]
Legal Entity Type of Counterparty [Domain]
Comprehensive loss:
Comprehensive Income (Loss), Net of Tax, Attributable to Parent [Abstract]
Deferred Tax Assets, Operating Loss Carryforwards
Deferred Tax Assets, Operating Loss Carryforwards, Total
Net operating loss carryforwards
Cybersecurity Risk Management Processes for Assessing, Identifying, and Managing Threats [Text Block]
Impairment of Long-lived Assets
Impairment or Disposal of Long-Lived Assets, Policy [Policy Text Block]
Effective state tax rate
Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Percent
State income taxes, net of federal benefit
State and local income taxes, net of federal income tax effect
Other income (expense):
Other Nonoperating Income (Expense) [Abstract]
Issuance of Series B redeemable convertible preferred stock in connection with the settlement of the tranche right liability, net of issuance costs, shares
Issuance Of Series B Redeemable Convertible Preferred Stock Net Of Preferred Stock Tranche Right Liability And Issuance Costs Shares
Issuance of series B redeemable convertible preferred stock net of preferred stock tranche right liability and issuance costs shares.
Entity Public Float
Entity Public Float
Accrued external research and development expenses
Accrued External Research And Development Expenses Current
Accrued external research and development expenses current.
Expected volatility
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate
Preferred Stock, Shares Authorized
Preferred stock, shares authorized
Issuance of Series B redeemable convertible preferred stock in connection with the settlement of the tranche right liability, net of issuance costs
Issuance Of Series B Redeemable Convertible Preferred Stock Net Of Preferred Stock Tranche Right Liability And Issuance Costs
Issuance of series B redeemable convertible preferred stock net of preferred stock tranche right liability and issuance costs.
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]
Operating lease liability
Deferred Tax Assets Operating Lease Liability
Deferred tax assets operating lease liability
Related Party Transaction [Line Items]
Revenue
Revenue from Contract with Customer [Text Block]
Entity Registrant Name
Entity Registrant Name
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax
Gross Unrealized Losses
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset,Transfers, Net
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset, Transfers, Net
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset, Transfers, Net, Total
Entity Voluntary Filers
Entity Voluntary Filers
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table]
Additional paid-in capital
Additional Paid in Capital
Additional Paid in Capital, Total
Subsequent Events [Abstract]
Cybersecurity Risk Management Positions or Committees Responsible [Flag]
Income tax expense or benefit
Income Tax Expense (Benefit)
Income Tax Expense (Benefit), Total
Measurement Frequency [Axis]
Adjustments To Additional Paid In Capital Share based Compensation To Related Party Recognition Value
Adjustments to additional paid in capital share based compensation to related party recognition value.
Stock-based compensation expense - related party
Proceeds from IPO
Proceeds from Issuance of Common Stock
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Entity Common Stock, Shares Outstanding
Concentration of Credit Risk and of Significant Suppliers
Concentration Risk, Credit Risk, Policy [Policy Text Block]
Accumulated Other Comprehensive Income (Loss), Net of Tax
Accumulated Other Comprehensive Income (Loss), Net of Tax, Total
Accumulated other comprehensive income (loss)
Payments to Acquire Property, Plant, and Equipment
Payments to Acquire Property, Plant, and Equipment, Total
Purchases of equipment
Assets
Total assets
Property, Plant and Equipment [Table]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Weighted-Average Remaining Contractual Term, Options exercisable December 31, 2025
Temporary Equity Conversion Of Convertible Preferred Stock To Common Stock, Shares
Temporary equity conversion of convertible preferred stock to common stock, shares.
Conversion of convertible preferred stock to common stock upon closing of initial public offering, shares
Conversion of convertible preferred stock to common stock upon closing of initial public offering, shares
Income Statement [Abstract]
Stock-based Compensation Expense
Share-Based Payment Arrangement [Policy Text Block]
Number of shares issued and sold (in shares)
Sale of stock, number of shares issued
Sale of Stock, Number of Shares Issued in Transaction
Stock Issued During Period, Shares, New Issues
Issuance of common stock from initial public offering, net of issuance costs, shares
Lease, Cost [Abstract]
Preferred Stock Authorized
Redeemable convertible preferred stock, shares authorized
Temporary Equity, Shares Authorized
Maruho
Maruho Co Ltd [Member]
Maruho Co., Ltd.
Net loss per share attributable to common stockholders, diluted
Earnings Per Share, Diluted
Earnings Per Share, Diluted, Total
Number of directors approval by stock holders
Number Of Directors Approval By Stock Holders
Number Of Directors Approval By Stock Holders
Schedule of Segment Reporting Information, by Segment [Table Text Block]
Schedule of Segment Net Loss, Including Disaggregated Components of Operating Expenses
Effective Income Tax Rate Reconciliation, Percent [Abstract]
Title and Position [Domain]
Property, Plant, and Equipment, Useful Life, Term, Description [Extensible Enumeration]
Estimated Useful Life, Term, Description
City Area Code
City Area Code
Series A And B Redeemable Convertible Preferred Stock
Series A and B Redeemable Convertible Preferred Stock [Member]
Series A and B redeemable convertible preferred stock.
Auditor Name
Auditor Name
Estimated interest or penalties recognized on uncertain tax positions
Income Tax Examination, Penalties and Interest Expense
Income Tax Examination, Penalties and Interest Expense, Total
Change in Accounting Principle, Accounting Standards Update, Early Adoption [true false]
Exercise of stock options, net of tax withholding
Stock Issued During Period Value Stock Options Exercised Net Of Tax Withholding
Stock issued during period value stock options exercised net of tax withholding.
Effective Income Tax Rate Reconciliation, Tax Credit, Research, Amount
Research and development tax credits
Research and development tax credits
Research And Development Program Expense
Research and development program expense.
Verekitug program
Variable Lease, Cost
Variable lease cost
Stock Issued During Period, Value, Employee Stock Purchase Plan
Issuance of common stock under employee stock purchase plan
Change in Fair Value of Preferred Stock Tranche Right Liabilities
Change in fair value of preferred stock tranche right liabilities.
Change in fair value of preferred stock tranche right liability
Change in fair value of preferred stock tranche right liability
Operating Lease, Weighted Average Remaining Lease Term
Weighted-average remaining lease term - operating leases
Segment Reporting Information [Line Items]
Stock split ratio
Stockholders' Equity Note, Stock Split, Conversion Ratio
Investor [Member]
Investor
Lease expired date
Lease Expiration Date
Lease, Cost
Total lease cost
Cash and Cash Equivalents
Cash and Cash Equivalents, Policy [Policy Text Block]
Payment Term of Invoicing
Payment term of invoicing.
Payment term of invoicing
Property and equipment, net
Property and equipment, net
Property, Plant and Equipment, Net
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Number
Number of Options, Vested and expected to vest December 31, 2025
Cash, cash equivalents and restricted cash at end of period
Cash, cash equivalents and restricted cash at beginning of period
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Including Discontinued Operation
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations, Total
Loss from operations
Operating Income (Loss)
Accumulated Deficit
Retained Earnings [Member]
Cash and Cash Equivalents [Axis]
Four Six Zero Totten Pond Road Waltham Massachusetts [Member]
460, Totten Pond Road Waltham Massachusetts [Member]
460 Totten Pond Road, Waltham, Massachusetts
Stock-based compensation expense
Share-Based Payment Arrangement, Noncash Expense
Share-Based Payment Arrangement, Noncash Expense, Total
Stock-based compensation
Accounts receivable - related party
Increase (Decrease) in Accounts and Notes Receivable
Accounts receivable
Offering costs
Payments of deferred offering costs
Payments of Stock Issuance Costs
Issuance costs
Increase in number of shares available for issuance
Share-Based Compensation Arrangement by Share-Based Payment Award Increase in Number of Shares Available for Issuance
Share-based compensation arrangement by share-based payment award, increase in number of shares available for issuance.
Net operating loss caryforwards expire year
Operating Loss Carryforwards Expiration Year
Operating loss carryforwards expiration year.
Weighted-average discount rate - operating leases
Operating Lease, Weighted Average Discount Rate, Percent
Operating lease liabilities, net of current portion
Operating Lease, Liability, Noncurrent
Operating Lease, Liability, Noncurrent, Total
Level 1
Fair Value, Inputs, Level 1 [Member]
Class of Stock [Line Items]
Net cash provided by financing activities
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation
Summary of Components of Lease Cost
Lease, Cost [Table Text Block]
Change in Accounting Principle, Accounting Standards Update, Adopted [true false]
Change in accounting principle accounting standards update adopted [true false]
Auditor Location
Auditor Location
Schedule of Dilutive Securities Excluded from Calculation of Diluted Net Loss per Share
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Corporate Debt Securities [Member]
Corporate Debt Securities
Income Tax Jurisdiction [Domain]
Debt Securities, Available-for-Sale [Table]
Entity Interactive Data Current
Entity Interactive Data Current
Deferred Tax Liabilities, Gross [Abstract]
Deferred tax liabilities:
Statement of Income Location, Balance [Domain]
Cash flows from operating activities:
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract]
Stock issued upon conversion
Number of preferred stock converted to Common stock
Convertible Preferred Stock, Shares Issued upon Conversion
Patent and Trademarks
Patent and Trademarks [Policy Text Block]
Patent and trademarks.
Non-cash lease expense
Non-cash Lease Expense
Non-cash Lease Expense
Net amortization of premiums and accretion of discounts on short-term investments
Accretion (Amortization) of Discounts and Premiums, Investments
Restricted Cash
Restricted Cash [Policy Text Block]
Restricted cash.
Cash and cash equivalents
Cash Equivalents, at Carrying Value
Cash Equivalents, at Carrying Value, Total
Entity Tax Identification Number
Entity Tax Identification Number
Share price
Per share fair value of common stock
Share Price
Local Phone Number
Local Phone Number
Related Party Transaction [Domain]
2024 Employee Stock Purchase Plan
Two thousand twenty four employee stock purchase plan.
Two Thousand Twenty Four Employee Stock Purchase Plan [Member]
Amortization of acquired IPR&D
Deferred Tax Assets Amortization Of Acquired
Deferred tax assets amortization of acquired
Other
Other Liabilities, Current
Unrecognized compensation cost related to unvested stock options
Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount
Short-Term Lease, Cost
Short-term lease cost
Auditor Opinion [Text Block]
2024 Stock Option and Incentive Plan
Two thousand twenty four stock option and incentive plan.
Two Thousand Twenty Four Stock Option and Incentive Plan [Member]
Accounting Policies [Abstract]
Disaggregation of Revenue [Line Items]
License agreement, revenue recognized
Revenue from Contract with Customer, Excluding Assessed Tax
Collaboration revenue
Earnings Per Share, Basic, by Common Class, Including Two-Class Method [Table]
General and Administrative Expense [Abstract]
General and administrative:
Class of Stock [Domain]
Number of remaining shares available for future grants
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant
Weighted average period in years of recognition for unvested stock options
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Office Equipment
Office Equipment [Member]
Accrued consultant and professional fees
Accrued Professional Fees, Current
Stock, Class of Stock [Table]
Cost reimbursements received
Related Party Transaction Cost Reimbursements Received
Related party transaction, cost reimbursements received.
Entity Emerging Growth Company
Entity Emerging Growth Company